Comparison of Angiomyofibroblastoma and Aggressive Angiomyxoma in Both Sexes: Four Cases Composed of Bimodal CD34 and Factor XIIIa Positive Dendritic Cell Subsets. Author links open overlay panel Jeffrey S. Silverman 1 2 Jak Albukerk 1 2 Ali Tamsen 1 2. Show more. Share. Cite.

The increased prothrombin protein level leads to a hypercoagulable state, i.e., an increased tendency to form blood clots. This G20210A mutation in the factor II

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They are subsets of mesenchymal cells, cancer-associated macrophages and antigen-presenting cells. Factor XIIIa-positive dendrocytes present at the periphery and inside epithelial neoplasms are an heterogeneous group of cells. They are subsets of mesenchymal cells, cancer-associated macrophages and antigen-presenting cells. Factor XIIIa positive control slides are intended for use as positive controls for immunohistochemical (IHC) staining using an anti-Factor XIIIa antibody. Physical form Paraffin embedded tissue section mounted on microscope slide Factor XIIIa-positive cells were most numerous in the dermis and connective tissues. Numerous large, stellate cells in placental villi, decidua, and chorionic membranes also expressed factor XIIIa at 7–9 weeks gestational age, before the onset of fetal hematopoiesis. Immunohistochemical analysis showed that factor XIIIa-positive histiocytic cells were distributed in the area without haemosiderin, but such cells were absent in the area with its deposition.

Cellular Localization: Cytoplasmic Positive Control: Dermatofibroma, placenta or skin Known Applications: Immunohistochemistry (formalin-fixed paraffin-embedded tissues) Supplied As: Buffer with protein carrier and preservative 1992-08-01 Factor XIIIa Activity Assay Kit (Fluorometric): Simple assay to measure activity Factor XIIIa. Includes Positive Control and Inhibitor (Iodoacetamide). 100 Assays Factor XIIIa was seen in 29 (97%) of 30 DFs (mean factor-XIIIa score, 4.1 +/- 0.3).

8 Feb 2018 Immunohistochemistry in Normal Skin: p63, EMA, desmin, SMA, CD34, Factor XIIIa. 6,282 views6.2K views. • Feb 8, 2018. 189. 0. Share. Save.

Factor XIIIa positive cells in human skin represent a specific population of bone marrow dermal dendritic cells, distinct from Langerhans cells which share some features common to mononuclear phagocytes. Factor XIIIa-positive dendrocytes are almost absent in the reticular dermis and markedly reduced in number and size in the adventitial dermis. By contrast, the densities of vimentin-positive cells and CD34-positive cells were unremarkable.

The increased prothrombin protein level leads to a hypercoagulable state, i.e., an increased tendency to form blood clots. This G20210A mutation in the factor II

1999-10-18 · FXIIIa is a 80 kDa subunit of the blood coagulation factor XIII, also found in cells belonging to the megakaryocyte/platelet and the monocyte/macrophage cell lineages (Adany, 1996).

1999-10-18 · FXIIIa is a 80 kDa subunit of the blood coagulation factor XIII, also found in cells belonging to the megakaryocyte/platelet and the monocyte/macrophage cell lineages (Adany, 1996). The aim of the present study was to evaluate the contribution of factor XIIIa (FXIIIa)-positive dermal dendritic cells to formation of keloids and hypertrophic scars. The numbers of FXIIIa-positive cells were counted in the keloid, hypertrophic scar and mature scar, each of which was divided into fibrocollagenous area and superficial dermal area overlying the nodular lesion. Factor XIIIa positive cells in human skin represent a specific population of bone marrow dermal dendritic cells, distinct from Langerhans cells which share some features common to mononuclear phagocytes. Dendritic, factor XIIIa positive cells were observed in all tissues studied, but were most numerous in skin and mucosal tissues (gastrointestinal tract, bladder). They were also observed associated with epithelial structures in lung and kidney, but were only rarely observed in liver, thyroid, testis and spleen. Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot.
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Cellular Localization: Cytoplasmic Positive Control: Dermatofibroma, placenta or skin Known Applications: Immunohistochemistry (formalin-fixed paraffin-embedded tissues) Supplied As: Buffer with protein carrier and preservative ical aid to the diagnosis of the most frequent type of EDS. Factor XIIIa-positive dendrocytes are almost absent in the reticular dermis and markedly reduced in number and size in the adventitial dermis.

We have also evaluated neurofilament in a number of these types of cases, and I have observed neu- DF stains positively for Factor XIIIa and negative for CD34, while DFSP stains oppositely with positive CD34 staining and negative Factor XIIIa staining. This differentiation is, however, not absolute, as there are reports of Factor XIIIa positive DFSPs and of CD34 positive DFs. Factor XIII deficiency is an extremely rare inherited blood disorder characterized by abnormal blood clotting that may result in abnormal bleeding.
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mnsotto@ajato.com.br . SOTTO, Mirian Nacagami - Dendrócitos dérmicos fator XIIIa positivos na resposta tecidual cutânea da … Comparison of Angiomyofibroblastoma and Aggressive Angiomyxoma in Both Sexes: Four Cases Composed of Bimodal CD34 and Factor XIIIa Positive Dendritic Cell Subsets. Author links open overlay panel Jeffrey S. Silverman 1 2 Jak Albukerk 1 2 Ali Tamsen 1 2. Show more. Share.